What is a Meta-Analysis? The benefits and challenges
Meta-analysis study flow diagram. A literature review of case-control
Τμήμα Οικονομικών Επιστημών
PPT
Meta-Analysis Methodology for Basic Research: A Practical Guide
Meta-Analysis and Case Study
COMMENTS
How to conduct a meta-analysis in eight steps: a practical guide
In a qualitative meta-analysis, the identified case studies are systematically coded in a meta-synthesis protocol, ... Wood JA (2008) Methodology for dealing with duplicate study effects in a meta-analysis. Organ Res Methods 11(1):79-95. Article Google Scholar Download references. Funding. Open Access funding enabled and organized by Projekt ...
Doing a Meta-Analysis: A Practical, Step-by-Step Guide
Practical steps: The weight for each study is calculated as: Weight = 1 / (within-study variance) For example: Let's say a study reports a within-study variance of 0.04. The weight for this study would be: 1 / 0.04 = 25. Calculate the weight for every study included in your meta-analysis using this method.
Systematic Reviews and Meta-Analysis: A Guide for Beginners
The graphical output of meta-analysis is a forest plot which provides information on individual studies and the pooled effect. Systematic reviews of literature can be undertaken for all types of questions, and all types of study designs. This article highlights the key features of systematic reviews, and is designed to help readers understand ...
Introduction to systematic review and meta-analysis
A systematic review collects all possible studies related to a given topic and design, and reviews and analyzes their results [ 1 ]. During the systematic review process, the quality of studies is evaluated, and a statistical meta-analysis of the study results is conducted on the basis of their quality. A meta-analysis is a valid, objective ...
Chapter 10: Analysing data and undertaking meta-analyses
Many judgements are required in the process of preparing a meta-analysis. Sensitivity analyses should be used to examine whether overall findings are robust to potentially influential decisions. Cite this chapter as: Deeks JJ, Higgins JPT, Altman DG (editors). Chapter 10: Analysing data and undertaking meta-analyses.
Case study meta‐analysis in the social sciences. Insights on data
5 LESSONS FOR DESIGN CHOICES IN CASE STUDY META-ANALYSIS. Data derived from our case survey proved largely robust, displaying high degrees of inter-rater reliability and agreement, and only limited effects of the distorting factors tested for. Based on these findings, we identify a number of critical design choices will influence the quality ...
Research Guides: Study Design 101: Meta-Analysis
This study looked at surgical outcomes including "blood loss, operative time, length of stay, complication and reoperation rates and functional outcomes" between patients with and without obesity. A meta-analysis of 32 studies (23,415 patients) was conducted. There were no significant differences for patients undergoing minimally invasive ...
How to Perform a Meta-analysis: a Practical Step-by-step Guide Using R
By typing forest (meta-analysis name), RStudio will create a forest plot of the meta-analysis. In this case type in the console: forest (metanalisetestex) If you want to omit the result/diamond of the fixed model from the forest plot (Figure 12), set the comb.fixed argument to false by typing the following command line in the console:
Meta-analysis: Principles and procedures
Meta-analysis is a statistical procedure that integrates the results of several independent studies considered to be "combinable."1 Well conducted meta-analyses allow a more objective appraisal of the evidence than traditional narrative reviews, provide a more precise estimate of a treatment effect, and may explain heterogeneity between the results of individual studies.2 Ill conducted ...
Meta-analysis and the science of research synthesis
Meta-analysis is the quantitative, scientific synthesis of research results. Since the term and modern approaches to research synthesis were first introduced in the 1970s, meta-analysis has had a ...
The 5 min meta-analysis: understanding how to read and ...
Tip 1: Know the type of outcome than. There are differences in a forest plot depending on the type of outcomes. For a continuous outcome, the mean, standard deviation and number of patients are ...
Systematic reviews vs meta-analysis: what's the difference?
A systematic review is an article that synthesizes available evidence on a certain topic utilizing a specific research question, pre-specified eligibility criteria for including articles, and a systematic method for its production. Whereas a meta-analysis is a quantitative, epidemiological study design used to assess the results of articles ...
Case study meta‐analysis in the social sciences. Insights on data
The method offers a meta-analytical tool to synthesize larger numbers of qualitative case studies, yielding data amenable to large-N analysis. However, resulting data is prone to specific threats to validity, including biases due to publication type, rater behaviour, and variable characteristics, which researchers need to be aware of.
Methodological quality and synthesis of case series and case reports
It is paramount to recognise that a systematic review and meta-analysis of case reports/series should not be placed at the top of the hierarchy in a pyramid that depicts validity.26 The certainty of evidence derived from a meta-analysis is contingent on the design of included studies, their risk of bias, as well as other factors such as ...
Meta-Synthesis of Qualitative Case Studies: An Approach to Theory
The meta-synthesis aims at building theory out of primary qualitative case studies that have not been planned as part of a unified multisite effect. By drawing on an understanding of research synthesis as the interpretation of qualitative evidence from a postpositivistic perspective, this article proposes eight steps of synthesizing existing ...
Frontiers
Finally, the meta-analysis will be conducted in the latest version of the statistical software RevMan. The Mantel-Haenszel method will be used for the fixed effects model if tests of heterogeneity are not significant. ... However, it is important to note that promoting the need to synthesize these types of studies (case reports/studies and case ...
A comprehensive meta-analysis and a case-control study give insights
A case-control analysis followed the meta-analysis in the East Indian sample population among smokers, which revealed no association of rs1048943A > G of CYP1A1 with overall lung cancer risk ...
Ten simple rules for carrying out and writing meta-analyses
Rule 2: Follow available guidelines for different types of meta-analyses. There are several available general guidelines. The first of such efforts were the Quality of Reports of Meta-analyses of Randomized Controlled Trials (QUORUM) [] and the Meta-analysis of Observational Studies in Epidemiology (MOOSE) statements [], but currently, the Preferred Reporting Items for Systematic reviews and ...
PDF Evidence Pyramid
Case-Control Study: A type of research that retrospectively compares characteristics of an individual who has a certain condition (e.g. hypertension) with one who does not (i.e., a matched control or similar ... Meta-Analysis: A process of using quantitative methods to summarize the results from multiple studies, obtained and critically ...
IGHLIGHTSRecent work has introduced a meta-analysis framework explicitly based in causal. inference, which transports results from a meta-analysis to a specific target po. e.This paper applies the recent meta-analysis framework to two cas. studies and. omparesthe results with those from well-esta.
Household Transmission of SARS-CoV-2: A Systematic Review and Meta
Findings In this meta-analysis of 54 studies with 77 758 participants, the estimated overall household secondary attack rate was 16.6%, higher than observed secondary attack rates for SARS-CoV and Middle East respiratory syndrome coronavirus. Controlling for differences across studies, secondary attack rates were higher in households from ...
Meta-Analysis
This study looked at surgical outcomes including "blood loss, operative time, length of stay, complication and reoperation rates and functional outcomes" between patients with and without obesity. A meta-analysis of 32 studies (23,415 patients) was conducted. There were no significant differences for patients undergoing minimally invasive ...
Subjective logic as a complementary tool to meta-analysis to explicitly
DOI: 10.1016/j.infbeh.2024.101978 Corpus ID: 271639522; Subjective logic as a complementary tool to meta-analysis to explicitly address second-order uncertainty in research findings: A case from infant studies.
Systematic Reviews and Meta-analysis: Understanding the Best Evidence
Meta-analyses are studies of studies. Meta-analysis provides a logical framework to a research review where similar measures from comparable studies are listed systematically and the available effect measures are combined wherever possible. The fundamental rationale of meta-analysis is that it reduces the quantity of data by summarizing data ...
Association of ACE and AGTR1 variants with retinopathy of ...
A total of 377 premature infants were enrolled in the study. The ACE variant was evaluated using PCR, and AGTR1 was assessed using TaqMan probes. Clinical characteristics, including risk factors and comorbidities, were documented. A meta-analysis of the effects of the studied variants on ROP was also conducted.
Gestational diabetes mellitus management according to ultrasound fetal
Random-effect model meta-analyses were used to minimize the effects of uncertainty associated with inter-study variability. Results are reported as standardized mean differences (SMDs) or as odds ratios (ORs) and their 95% confidence interval (CI). Heterogeneity between studies was estimated using the I 2 statistic. The Cochrane Risk of Bias ...
Meta-analysis in medical research
Meta-Analysis and Systematic Review. Glass first defined meta-analysis in the social science literature as "The statistical analysis of a large collection of analysis results from individual studies for the purpose of integrating the findings" 9.Meta-analysis is a quantitative, formal, epidemiological study design used to systematically assess the results of previous research to derive ...
Effectiveness and safety of switching from oral antipsychotics to Once
Background: Considering the improvement in adherence and convenience, once-monthly paliperidone palmitate (PP1M) has been increasingly used in the treatment of schizophrenia. However, the outcomes for patients who switch from oral antipsychotics (OAPs) to PP1M have not been reliably assessed. The objective of this systematic review and meta-analysis was to investigate the efficacy and safety ...
IMAGES
COMMENTS
In a qualitative meta-analysis, the identified case studies are systematically coded in a meta-synthesis protocol, ... Wood JA (2008) Methodology for dealing with duplicate study effects in a meta-analysis. Organ Res Methods 11(1):79-95. Article Google Scholar Download references. Funding. Open Access funding enabled and organized by Projekt ...
Practical steps: The weight for each study is calculated as: Weight = 1 / (within-study variance) For example: Let's say a study reports a within-study variance of 0.04. The weight for this study would be: 1 / 0.04 = 25. Calculate the weight for every study included in your meta-analysis using this method.
The graphical output of meta-analysis is a forest plot which provides information on individual studies and the pooled effect. Systematic reviews of literature can be undertaken for all types of questions, and all types of study designs. This article highlights the key features of systematic reviews, and is designed to help readers understand ...
A systematic review collects all possible studies related to a given topic and design, and reviews and analyzes their results [ 1 ]. During the systematic review process, the quality of studies is evaluated, and a statistical meta-analysis of the study results is conducted on the basis of their quality. A meta-analysis is a valid, objective ...
Many judgements are required in the process of preparing a meta-analysis. Sensitivity analyses should be used to examine whether overall findings are robust to potentially influential decisions. Cite this chapter as: Deeks JJ, Higgins JPT, Altman DG (editors). Chapter 10: Analysing data and undertaking meta-analyses.
5 LESSONS FOR DESIGN CHOICES IN CASE STUDY META-ANALYSIS. Data derived from our case survey proved largely robust, displaying high degrees of inter-rater reliability and agreement, and only limited effects of the distorting factors tested for. Based on these findings, we identify a number of critical design choices will influence the quality ...
This study looked at surgical outcomes including "blood loss, operative time, length of stay, complication and reoperation rates and functional outcomes" between patients with and without obesity. A meta-analysis of 32 studies (23,415 patients) was conducted. There were no significant differences for patients undergoing minimally invasive ...
By typing forest (meta-analysis name), RStudio will create a forest plot of the meta-analysis. In this case type in the console: forest (metanalisetestex) If you want to omit the result/diamond of the fixed model from the forest plot (Figure 12), set the comb.fixed argument to false by typing the following command line in the console:
Meta-analysis is a statistical procedure that integrates the results of several independent studies considered to be "combinable."1 Well conducted meta-analyses allow a more objective appraisal of the evidence than traditional narrative reviews, provide a more precise estimate of a treatment effect, and may explain heterogeneity between the results of individual studies.2 Ill conducted ...
Meta-analysis is the quantitative, scientific synthesis of research results. Since the term and modern approaches to research synthesis were first introduced in the 1970s, meta-analysis has had a ...
Tip 1: Know the type of outcome than. There are differences in a forest plot depending on the type of outcomes. For a continuous outcome, the mean, standard deviation and number of patients are ...
A systematic review is an article that synthesizes available evidence on a certain topic utilizing a specific research question, pre-specified eligibility criteria for including articles, and a systematic method for its production. Whereas a meta-analysis is a quantitative, epidemiological study design used to assess the results of articles ...
The method offers a meta-analytical tool to synthesize larger numbers of qualitative case studies, yielding data amenable to large-N analysis. However, resulting data is prone to specific threats to validity, including biases due to publication type, rater behaviour, and variable characteristics, which researchers need to be aware of.
It is paramount to recognise that a systematic review and meta-analysis of case reports/series should not be placed at the top of the hierarchy in a pyramid that depicts validity.26 The certainty of evidence derived from a meta-analysis is contingent on the design of included studies, their risk of bias, as well as other factors such as ...
The meta-synthesis aims at building theory out of primary qualitative case studies that have not been planned as part of a unified multisite effect. By drawing on an understanding of research synthesis as the interpretation of qualitative evidence from a postpositivistic perspective, this article proposes eight steps of synthesizing existing ...
Finally, the meta-analysis will be conducted in the latest version of the statistical software RevMan. The Mantel-Haenszel method will be used for the fixed effects model if tests of heterogeneity are not significant. ... However, it is important to note that promoting the need to synthesize these types of studies (case reports/studies and case ...
A case-control analysis followed the meta-analysis in the East Indian sample population among smokers, which revealed no association of rs1048943A > G of CYP1A1 with overall lung cancer risk ...
Rule 2: Follow available guidelines for different types of meta-analyses. There are several available general guidelines. The first of such efforts were the Quality of Reports of Meta-analyses of Randomized Controlled Trials (QUORUM) [] and the Meta-analysis of Observational Studies in Epidemiology (MOOSE) statements [], but currently, the Preferred Reporting Items for Systematic reviews and ...
Case-Control Study: A type of research that retrospectively compares characteristics of an individual who has a certain condition (e.g. hypertension) with one who does not (i.e., a matched control or similar ... Meta-Analysis: A process of using quantitative methods to summarize the results from multiple studies, obtained and critically ...
IGHLIGHTSRecent work has introduced a meta-analysis framework explicitly based in causal. inference, which transports results from a meta-analysis to a specific target po. e.This paper applies the recent meta-analysis framework to two cas. studies and. omparesthe results with those from well-esta.
Findings In this meta-analysis of 54 studies with 77 758 participants, the estimated overall household secondary attack rate was 16.6%, higher than observed secondary attack rates for SARS-CoV and Middle East respiratory syndrome coronavirus. Controlling for differences across studies, secondary attack rates were higher in households from ...
This study looked at surgical outcomes including "blood loss, operative time, length of stay, complication and reoperation rates and functional outcomes" between patients with and without obesity. A meta-analysis of 32 studies (23,415 patients) was conducted. There were no significant differences for patients undergoing minimally invasive ...
DOI: 10.1016/j.infbeh.2024.101978 Corpus ID: 271639522; Subjective logic as a complementary tool to meta-analysis to explicitly address second-order uncertainty in research findings: A case from infant studies.
Meta-analyses are studies of studies. Meta-analysis provides a logical framework to a research review where similar measures from comparable studies are listed systematically and the available effect measures are combined wherever possible. The fundamental rationale of meta-analysis is that it reduces the quantity of data by summarizing data ...
A total of 377 premature infants were enrolled in the study. The ACE variant was evaluated using PCR, and AGTR1 was assessed using TaqMan probes. Clinical characteristics, including risk factors and comorbidities, were documented. A meta-analysis of the effects of the studied variants on ROP was also conducted.
Random-effect model meta-analyses were used to minimize the effects of uncertainty associated with inter-study variability. Results are reported as standardized mean differences (SMDs) or as odds ratios (ORs) and their 95% confidence interval (CI). Heterogeneity between studies was estimated using the I 2 statistic. The Cochrane Risk of Bias ...
Meta-Analysis and Systematic Review. Glass first defined meta-analysis in the social science literature as "The statistical analysis of a large collection of analysis results from individual studies for the purpose of integrating the findings" 9.Meta-analysis is a quantitative, formal, epidemiological study design used to systematically assess the results of previous research to derive ...
Background: Considering the improvement in adherence and convenience, once-monthly paliperidone palmitate (PP1M) has been increasingly used in the treatment of schizophrenia. However, the outcomes for patients who switch from oral antipsychotics (OAPs) to PP1M have not been reliably assessed. The objective of this systematic review and meta-analysis was to investigate the efficacy and safety ...